Radio-isotope investigations in primary myeloid metaplasia
نویسندگان
چکیده
منابع مشابه
Radio-isotope investigations in primary myeloid metaplasia.
Chromium-51 and iron-59 studies in patients with primary myeloid metaplasia show that the anaemia of the condition is dependent on depression of marrow activity, aggravated in about one-third of cases by accelerated red cell destruction to which the marrow compensatory response is inadequate. Surface measurements of isotope activity assist in assessing dependence on extramedullary sites for ery...
متن کاملSplenectomy in myeloid metaplasia.
Between 1960 and 1977, 50 patients with agnogenic myeloid metaplasia were splenectomized. Twenty-five of 26 patients with painful splenomegaly, 4 of 9 patients with refractory hemolytic anemia, 4 of 10 patients with refractory thrombocytopenia, and 4 of 4 patients with portal hypertension showed significant benefit from the procedure. There were five immediate postoperative deaths. Four of thes...
متن کاملMyelofibrosis with myeloid metaplasia (MMM), Idiopathic myelofibrosis, Agnogenic myeloid metaplasia
MMM usually presents with fatigue, weight loss, splenomegaly with or without symptoms. Anemia and various alterations of the white blood cell and/or platelet count are frequently seen at diagnosis. Thrombocytopenia-related bleeding may occur. MMM must be distinguished from myelodysplasia with fibrosis, from acute megakayoblastic leukemia and acute myelofibrosis. As the disease progresses, incre...
متن کاملBusulfan therapy in myeloid metaplasia.
By NOBORU Oism, SCOTT N. SWISHER AND STANLEY B. Tu0UP B USULFAN#{176} ( i,4-dirnethanesulphon loxybutanc ) is a radiomimetic agent which appears to inhibit cellular metabolism through its ability to alkylate nuclcoproteins.11 Cells undergoing division seem particularly susceptible to the action of busulfan. Since it was synthesized by Haddow and Timmis,4 husulfan has been successfully used in t...
متن کامل[Myelofibrosis with myeloid metaplasia].
Introduction Myelofibrosis with myeloid metaplasia (MMM) represents both agnogenic myeloid metaplasia (AMM) and the fibrotic stages of polycythemia vera (PV) and essential thrombocythemia (ET). The latter two conditions are also referred to as post polycythemic myelofibrosis (PPM) and post thrombocythemic myelofibrosis (PTM). MMM is currently classified under the broad category of chronic myelo...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Clinical Pathology
سال: 1961
ISSN: 0021-9746
DOI: 10.1136/jcp.14.6.595